纳洛酮联合醒脑静注射液治疗急性重度酒精中毒87例的疗效观察

目的探讨纳洛酮联合醒脑静注射液治疗急性重度酒精中毒的临床效果。方法87例急性重度酒精中毒患者被随机分为实验组(n=45)和对照组(n=42),2组均给予基础治疗,对照组给予纳洛酮治疗方案,实验组给予纳洛酮联合醒脑静治疗方案。结果2组总有效率、痊愈率、酒后清醒时间和酒后症状消失时间等方面均有显著性差异(P<0.05),实验组疗效显著优于对照组。结论纳洛酮联合醒脑静注射液治疗急性重度酒精中毒,能显著提高疗效,缩短恢复时间,值得在临床上应用和推广。

Objective To explore the curative effect of naloxone combined with xingnaojing used in acute severe alcoholism. Methods 87 cases of patients with acute severe alcoholism were randomly divided into experimental group （n=45） and control group （n=42）. Both groups were given based treatment, control group were given naloxone therapy, and experimental group were given naloxone combined with xingnaojing therapy. Results The total effective rate, cure rate, time of clear-headed and vanishing of symptom after alcohol in experimental group were significantly better than that in control group（P〈0.05）. Conclusion Naloxone combined with xingnaojing used in acute severe alcoholism can significantly enhance clinical effect and shorten recovery time, so it deserved application and promotion in clinical work.