高原地区141例原发性肺癌临床及病理分析

Clinical and Pathological Analysis of 141 Cases of Primary Lung Cancer at High Altitude

目的:分析青海高原地区原发性肺癌的发病情况及病理特点,探讨影响预后的因素。方法:本文分析了141例肺癌患者发病率,临床病理情况及随访材料。结果:原发性肺癌患者男87例,女54例,年龄最小为27岁,最大为86岁。肺癌患者发病年龄高。男性患者多于女性患者。病理学解剖分型:中央型肺癌多见,病理学镜下分型鳞癌多见。从5年生存率来看:世居患者为40.8%,移居者为24.3%,世居患者要好于移居患者(2=4.397,P<0.05);城镇患者为45%,农村患者为28%,城镇患者要好于农村患者(2=4.1,P<0.05)。结论:高原地区肺癌致病因素多,预后情况复杂,还需进一步研究。

Objecive：To charactrize the incidence and Qinghai -Tibet plateau region and its the influnence factors pathological characteristics of primary lung cancer in of the prognosis. Methods：Retrospective documents of 141 cases of lung cancer （ 87 men, 54 women）, including incidence, clinical, pathological and follow- up materials, were revewedo Results：Patients 27 and 86 were the youngest and the oldest people in this report. And older patients had higher incidence of the lung cancer, and male patients were more than female patients. The central type of lung cancer and squamous cell carcinoma were occurred mostly in our study. The five - year survival rate of the patients with lung cancer was higher in the native persons than that in migrants（40.8% vs 24.3% ,P 〈0.05）. As well higher survival rate was in city persons than in rural persons （45% vs 28%, P 〈 0.05 ）. Conclusions： Pathogenic factors of primary lung cancer at high altitude are so many, and prognosis is so complex. Our results suggeet that it need to be further studied.