摘要
信号转导和转录激活因子3(STAT3)是细胞内关键性的信号转导蛋白,在肿瘤细胞的增殖、去分化以及肿瘤的侵袭、转移中起重要作用。研究发现,在胰腺癌、乳腺癌、肺癌、前列腺癌、宫颈癌等肿瘤中均有STAT3的异常表达。现就STAT3蛋白的生物学特性、与肿瘤的关系及其在宫颈癌中的研究现状予以综述。
Signal transducer and activator of transcription3（STAT3）is an important signal transductional protein in cell and is closely associated with the proliferation,dedifferentiation,invasion and metastasis of in many tumor tissue,such as pancreatic cancer,breast cancer,lung cancer,prostatic cancer and cervical cancer,and so on.This article reviewed the characteristics of molecular biology,the relations with tumor and the progress of STAT3 gene in cervical cancer.
出处
《医学综述》
2010年第7期1022-1024,共3页
Medical Recapitulate
关键词
信号转导和转录激活因子3
宫颈
肿瘤
Signal transducer and activator of transcription3
Cervical
Tumor
