摘要
胃癌合并卵巢转移在临床上并不少见,也是导致女性胃癌患者治疗失败的主要原因之一。胃癌卵巢转移多见于40~50岁绝经前妇女,其最可能的发病机制是胃癌的逆行性淋巴道转移。胃癌卵巢转移的诊断要点包括既往或同时的胃癌病史和发现双侧卵巢实性肿瘤。治疗以根治性切除原发瘤和转移灶为主,并辅助化疗、放疗、内分泌治疗等综合治疗。胃癌卵巢转移多预后不良,根治性手术可改善预后,提高生存率。
Ovarian metastasis of gastric cancer is not rare in clinical practice and also one of the major causes leading to the treatment failure in female gastric cancer patients.Ovarian metastasis of gastric cancer occurs in premenopausal women aged from 40 to 50 years old.The diagnostic key points consist of the previous or concomitant history of gastric cancer and the detection of bilateral ovarian solid tumors.The therapeutic regimens consist mainly of the radical resection of primary tumors and metastatic foci and the comprehensive treatment with adjuvant chemotherapy,radiotherapy and endocrine therapy.Ovarian metastasis of gastric cancer indicates the poor prognosis while the radical operation can improve the prognosis and survival.
出处
《医学综述》
2010年第7期1034-1037,共4页
Medical Recapitulate
关键词
胃癌卵巢转移
发病机制
临床病理特征
治疗
Ovarian metastasis of gastric cancer
Pathogenesis
Clinicopathologic characteristics
Treatment