电针刺激“曲池”“足三里”穴对自发性高血压大鼠血压及胰岛素抵抗的影响

Effect of Needling Quchi and Zusanli on Blood Pressure and Insulin Resistance in Spontaneously Hypertensive Rates

目地:观察电针刺激"曲池"、"足三里"穴对自发性高血压大鼠(SHR)血压和胰岛素抵抗(Insulin resistance,IR)的影响。方法:取12周龄24只SHR随机分为电针组、模型组和西药组3组,另取WKY大鼠8只为正常对照组,治疗2周后进行血压、空腹血糖(G)、胰岛素(I,放免法测定)、G/I、血脂的比较。结果:西药组和电针组大鼠的血压较模型组明显下降,各组SHR大鼠的G/I均明显低于WKY,电针组和西药组的G/I较模型组有所升高,TG、LDL-C较模型组有所降低(P<0.05)。结论:电针刺激"曲池"、"足三里"穴降低SHR大鼠血压的同时能够显著改善其伴随的IR。

Objective ： Effect of needling Quchi and Zusanli on blood pressure （ BP ） and insulin resistance （ IR ） in spontaneously hypertensive rats （ SHR ） was observe. Methods ： Twenty-four SHR aged 12 weeks were divided into three groups treated with western medicine, electro-acupuncture, and nothing as compared with age-matched eight Wister-Kyoto rats （ WKY ）. BP, glucose （ G ） and insulin （ I ） of fasting, G/I and blood lipid were measured treated 2 weeks and com pared among groups.Results： The western medicine group and the electro-acupuncture group than the blood pressure of rats in model group decreased SHR rats in each group G / I were significantly lower than the WKY, electro-acupuncture group and western medicine group G / I lower than the model group, TG, LDL-C higher than the model group has. Conclusion ： While needling Quehi and Zusanli lowered BP in SHR, it could improve attendant IR notably.