甲型流感的抗感染药物治疗

Anti-infective medicine for influenza A

在甲型H1N1流感中,准确判断患者病情的严重程度和继发性感染的可能,是合理使用抗病毒药物或抗菌药物治疗的关键环节。流感最常见的继发性感染病原为肺炎链球菌,A、C及G组链球菌,流感嗜血杆菌和金黄色葡萄球菌等,常造成病情恶化甚至死亡。在充分考虑抗菌药物治疗过程中可能出现的甲氧西林耐药金葡菌和难辨梭菌相关性腹泻的前提下,本文对甲型流感继发性感染的用药提出了具体治疗方案。

Accurate assessment of severity and risk of secondary infections of influenza A （H1N1） is undoubtedly the key critical process when making decisions about antiviral and antibiotic therapy.Secondary infections with Streptococcus pneumoniae,Streptococcus A,C and G group,Haemophilus influenzae and Staphylococcus aureus are likely to be the important causes of morbidity and mortality.The article considered the risk of Clostridium difficile-associated diarrhoea （CDAD） and the emergence of methicillin-resistant Staphylococcus aureus （MRSA）,and put forward the potentially useful antibiotic regimens for bacterial infections in influenza A （H1N1） and seasonal influenza.