石棉肺COPD急性加重期CRP检测的临床分析

Clinical Analysis of CRP Detection in Acute Stage of COPD Complicated by Asbestosis

目的探讨石棉肺慢性阻塞性肺疾病(COPD)急性加重期(AECOPD)患者治疗前后C-反应蛋白(CRP)变化及临床意义。方法对38例石棉肺COPD患者急性加重期治疗前后CRP的检测结果进行统计学分析。结果石棉肺AECOPD患者CRP在治疗前后差异具有统计学意义(P<0.01)。结论CRP可以作为石棉肺COPD早期的炎性指标,指导临床抗生素的应用。

[Objective]To investigate the changes of C-reactive protein （CRP） in the acute exacerbation of chronic obstructive pulmonary disease （AECOPD） complicated by asbestosis before and after treatment and its clinical significance.[Methods]The CRP detection results of 38 cases of AECOPD were compared before and after treatment.[Results]The difference of CRP results of AECOPD patients was significant before and after treatment（P〈0.01）.[Conclusion]CRP can be taken as inflammatory index at early stage of COPD,which can guide the clinical application of antibiotics.