母婴间血清叶酸、VB_(12)营养状况的配对研究

MATCHED SURVEY OF SERUM FOLIC ACID AND VITAMIN B_(12) BETWEEN PREGNANT WOMEN AND THEIR NEONATES

目的：研究末期妊娠孕母及初生婴儿血清叶酸、VB12含量的相关情况。方法：叶酸、VB12放射免疫测定法。结果：末期妊娠妇女叶酸缺乏发生率高（48．39％）。初生婴儿叶酸缺乏也普通。孕母VB12正常与否其相应初生婴儿脐血VB12含量差异有显著性，孕母正常组初生婴儿脐血VB12明显高于孕母降低组。结论：常规测定本期孕妇血清叶酸JB12含量，对明显低于正常者，应予以适当补充治疗。

Objective: To study the relationship of serum folic acid (FA) and Vitamin B12 (VB12) levels between full term pregnancy women and their neonates. Methods: Levels of serum FA and VB12 were detected by immunoassay. Results: The high incidence of FA deficiency (48. 39% ) in full term pregnancy women resulted in the general FA deficency in neonates. The VB12 level in matemal serum had strong positive correlation with that in neonatal umbilical blood. Conclusions: Measurement of the levels of serum FA and VB12 was necessary for pregnant women. Pregnant women whose levels of serum FA and VB12 are lower than normal should be supplemented with FA and VB12.