脂质分子通过自组装合成不同形貌的介孔材料(英文)

Mesoporous Silica with Different Morphology Synthesized by Self-assembling of Lipid Molecule

主要描述了通过氨基酸分子自组装来制备四种不同形貌的介孔硅材料,并通过常用的检测仪器:电子显微镜进行结构解析。已经发现:(1)通过改变反应温度从0,10,15到20°C,可以制备得到不同形貌的介孔材料,即类似于蛋白质分子的螺旋飘带,空心球,飞碟状和手性棒状形貌的二氧化硅介孔材料;(2)在螺旋飘带和空心球形貌材料中介孔孔道排列是无序的,而在飞碟和手性棒状材料中介孔孔道是高度有序排列的;(3)螺旋飘带形貌的材料是纯左手的,而手性棒状形貌的材料是右手过剩的介孔材料。该研究将为在分子水平合成手性材料提供一种新的方法。

This article describes one approach based upon the molecular self-assembly of lipids （N-acyl amino acid） to form various mesoporous microstructured silicas, together with a general approach for the structural analysis by electron microscopy. It has been found that, （1） the microstructure of the mesoporous silicas has been changed from helical ribbon （HR） analogous to folded proteins （Protein α/β helix）, hollow sphere, disk-like and chiral hexagonal rod with increasing synthesis temperature from 0 to 10, 15 and to 20 ℃; （2） the ammonium group functionalized disordered mesopores in the wall of HR and hollow sphere, and highly ordered straight and chiral 2d-hexagonal mesopores in the disk-like and helical rod have been observed, respectively; （3） the helical mesoporous ribbon silica was exclusively left-handed and the 2d-hexagonal chiral mesoporous silica was right-handed excess when 1 form N-acyl aminoacid has been used as lipid template. Findings could lead to a new insight into the formation of chiral materials at the molecular level and would facilitate a more efficient and systematic approach to generating rationalized chiral libraries.