妊娠合并糖尿病酮症酸中毒

Pregnancy associated diabetic ketoacidosis

妊娠合并糖尿病酮症酸中毒是临床急重症，孕妇及胎儿均有较高的死亡率。该文回顾分析文献，对妊娠合并糖尿病酮症酸中毒病理生理学及其处理方法进行深入地分析。并就孕期酮症酸中毒的发生率及其易发因素作一探讨，论述该病对妊娠的影响，孕妇的生理改变是妊娠合并糖尿病酮症酸中毒的发病基础，其治疗包括应用胰岛素及细致的补液疗法。及时的诊断和治疗能够显著地改善预后。

Pregnancy associated diabetic ketoacidosis （DKA） remains an emergent and severe condition in clinic with high maternal and fetal mortality. This article reviewed the literatures and analysed pathophysiology and management of DKA .Also,this article investigated incidence of DKA and influencing factors,and its impacts to the pregnancy.It was indicated that physiological changes of the pregnant woman is the base for development of DKA. Treatment for the patient with DKA includes insulin therapy and careful fluid replacement therapy. Early identification and timely treatment can markedly improve outcome of the patient. .