北京多中心社区良性前列腺增生患病率调查：BPC—BPH研究结果

Prevalence of benign prostatic hyperplasia in Beijing： a multicentre community-based cross-sectional survey

目的调查北京地区BPH患病现状。方法采用分层多阶段整群不等比例随机抽样方法选择年龄≥50岁男性作为研究对象，分别记录IPSS、腹部B超测量前列腺体积和剩余尿量、测定Qmax。结果进行方差分析。结果符合标准的研究对象共1644名男性，平均年龄64．5（50～93）岁，IPSS（9．9±8．2）分，前列腺体积平均（30．8±19．4）ml，Qmax平均（14．7±7．5）ml／s，三者与年龄有相关性。中一重度下尿路症状患病率50．8％（835／1644），69．7％（1146／1644）的被调查者前列腺总体积〉20ml，Qmax〈15ml／s占53．8％（883／1642）。以IPSS〉7分、前列腺体积〉20ml、Qmax；〈15ml／s为界，本组BPH患病率为26．8％（441／1644）。结论北京地区≥50岁男性下尿路症状、前列腺体积与年龄正相关，Qmax与年龄负相关，本组BPH患病率为26．8％，较以往增加。

Objective To investigate the prevalence of benign prostatic hyperplasia （BPH） in Beijing. Methods A cross-sectional study was performed at Beijing communities in men aged over 50 years. The international Prostate Symptom Score （IPSS） questionnaire was used to evaluate the symptoms. Transabdominal ultrasonography was used to measure prostate size and the residual urine volume（RUV）. Uroflowmetry was performed to record the maximum flow（Qmax）. One-way ANOVA was used to analysis the differences. Results 1644 subjects were enrolled and the mean age was 64.5 years （range 50--93 years）. The mean IPSS, prostate weight and Qmax were 9.9±8.2, （30.8± 19.4） and （14. 7 ± 7. 5） ml/s, respectively. They had correlation with age （r = 0. 388, 0. 262, -0. 371）. The prevalence of moderate-severe lower urinary tract symptoms （LUTS） was 50. 8% （835/1644）. Prostate volume was greater than 20 ml in 69.7%（1146/1644） of the subjects. Qmax was less than 15 ml/s in 53.8 % （883/1642） of the subjects. Conclusions In men age over 50 years in Beijing, there is positive correlation between LUTS, prostate size and age, and negative correlation between Q and age. The prevalence of BPH, defined as IPSS greater than 7, maxium flow rate less than 15 ml/s and prostate size greater than 20 ml, is 26.8%（441/1644）.