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外源性抗原诱导内皮细胞增殖及其MICA分子的表达 被引量:1

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摘要 MHC—I类相关链A(MICA)位于人类第6号染色体,属于非经典HLA—I类基因家族。抗MICA抗体与肾移植排斥反应相关及影响移植肾长期存活的观点已得到学者的广泛认同。MICA分子在移植物血管内皮细胞表达,特别是在内皮细胞膜蛋白的表达,增加了MICA抗原在移植受者体内成为抗移植物靶目标的可能性。
出处 《中华泌尿外科杂志》 CAS CSCD 北大核心 2010年第3期211-212,共2页 Chinese Journal of Urology
基金 国家自然科学基金资助项目(30872530) 江苏省自然科学基金资助项目(BK2007056) 江苏省卫生厅重点人才资助项目(RC2007079)
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参考文献5

  • 1Zou Y, Stastny P, Susal C, et al. Anti bodies against MICA antigens and kid hey transplant rejection. N Engl J Med 2007, 357: 1293-1300.
  • 2侯建全,何军,袁晓妮,鲍晓晶,邱桥成,王乾,钟健,诸明,温端改.动态分析HLA和MICA特异性抗体对移植肾功能的影响[J].中华泌尿外科杂志,2008,29(11):755-758. 被引量:6
  • 3Stastny P, Zou Y, Fan Y, et al. The emerging issue of MICA antibodies:an tibodies to MICA and other antigens of endothelial cells. Contrib Nephrol, 2009, 162:99-106.
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  • 5Seller M, Brabcova I, Vildicky O, et al. Heightened expression of the cytotoxic ity receptor NKG2D correlates with a cute and chronic nephropathy after kid ney transplantation. Am J Transplant, 2007, 7:423 -433.

二级参考文献9

  • 1Flegel WA. Will MICA glitter for recipients of kidney trans plants? N Engl J Med, 2007,357: 1337-1339.
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  • 4Zou Y, Stastny P, Susal C, et al. Antibodies against MICA antigens and kidney-transplant rejection. N Engl J Med, 2007, 357: 1293-1300.
  • 5Lee PC, Terasaki PI, Takemoto SK, et al. All chronic rejection failures of kidney transplants were preceded by the development of HLA antibodies. Transplantation, 2002, 74: 1192-1194.
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  • 7Jin YP, Jindra PT, Gong KW, et al. Anti-HLA class I anti- bodies activate endothelial cells and promote chronic rejection. Transplantation, 2005, 79(3 Suppl): 19-21.
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  • 9Yang CW, Oh EJ, Lee SB, et al. Detection of donor-specific anti HLA class Ⅰ and Ⅱ antibodies using antibody monitoring system. Transplant Proc, 2006, 38: 2803-2806.

共引文献5

同被引文献11

  • 1邹勇,宁琴(审校).NK细胞受体与配体的特异识别[J].国际免疫学杂志,2007,30(3):194-198. 被引量:3
  • 2Zou Y, Stastny P, Siisal C, et al. Antibodies against MICA Antigens and Kidney-Transplant Rejection. N ENGL J MED, 2007, 357(13) : 1293-1300.
  • 3Stastny P, Zou Y, Fan Y, et al. The emerging issue of MICA antibodies: antibodies to MICA and other antigens of endothelial cells. Contrib Nephrol, 2009, 162(1 ) : 99-106.
  • 4Zou Y, Stastny P. Role of MICA in the immune response to transplants. Tissue Antigens, 2010, 76 ( 3 ) : 171-176.
  • 5Vivier E, Tomasello E, Baratin Met al. Functions of natural killer cells. Nat Immunol, 2008, 9(5) : 503-510.
  • 6Gonzalez S, Lopez-Soto A, Suarez-Alvarez B, et al. NKG2D ligands: key targets of the immune response.. Trends Immunol, 2008, 29(8) : 397-403.
  • 7Suarez-Alvarez B, Lopez-Vazquez A, Diaz-Molina B, et al. The predictive value of soluble major histocompatibility complex class I chain-related molecule A (MICA) levels on heart allograft rejection. Transplantation, 2006, 82(3): 354-361.
  • 8Seller M, Brabcova I, Viklieky O, et al. Heightened expression of the cytotoxicity receptor NKG2D correlates with acute and chronic nephropathy after kidney transplantation. Am J Transplant, 2007, 7(2) : 423-433.
  • 9DuquesnoyRJ 李幼平 主编.移植免疫生物学[M].北京:科学出版社,2000.269-281.
  • 10侯建全,何军,袁晓妮,鲍晓晶,邱桥成,王乾,钟健,诸明,温端改.动态分析HLA和MICA特异性抗体对移植肾功能的影响[J].中华泌尿外科杂志,2008,29(11):755-758. 被引量:6

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