气相色谱法测定化妆品中二甘醇的含量及其测量不确度评定

DETERMINATION OF DIETHYLENE GLYCOL IN COSMETIC BY GC AND EVALUATION OF ITS UNCERTAINTY

采用气相色谱法测定了化妆品中的二甘醇，并用计量学方法对测量不确定度进行了评定。结果显示，二甘醇含量在0．01-0．1mg／mL范围内与色谱峰面积呈线性关系，线性相关系数为0．9999，检测限为0．41ug／mL，不同类别的3种样品中二甘醇测定结果的相对标准偏差在0．24％-1．52％范围内（n=6），平均回收率在93．65％～104．36％之间。当睹喱水样品中二甘醇的测定结果为48．1mg／kg时，其扩展不确定度为1．4mg／kg。该方法可用于化妆品中二甘醇含量的质量控制。

The diethylene glycol（DEG） in cosmetic was determined by GC, and the determination uncertainty was evaluated by metrological method. The test results indicated that in the DEG content range of 0.01 -0. 1 mg/mL, the linear correlation coefficient was 0.999 9, the limit of detection （LOD） was 0.41ug/mL, the RSD was 0.24% - 1.52% （ n = 6）, and the average recovery was 93.65% - 104.36% for three kind of samples. When the content of DEG in hair jelly was 48.1 mg/kg, the expanded uncertainty was 1.4 mg/kg. This method can be used to control the content of DEG in cosmetic samples.