顶空气相色谱法测定聚氯乙烯固体药用硬片中氯乙烯单体含量的测量不确定度评定

UNCERTAINTY EVALUATION OF DETERMINATION OF VCM IN PVC SHEET FOR SOLID PHARMACEUTICAL PACKAGING BY HEADSPACE GAS CHROMATOGRAPHY

依据CNAS-GL06,对顶空气相色谱法测定聚氯乙烯固体药用硬片中氯乙烯单体含量的测量不确定度进行系统分析,找出影响测量结果不确定度的主要因素。对各不确定度分量进行了评定和量化,计算了合成标准不确定度和扩展不确定度,聚氯乙烯固体药用硬片中氯乙烯单体含量的测定结果表示为(4.17±0.18)×10-7,k=2。

According to CNAS - GL06, the determination uncertainty of VCM in PVC sheet for solid pharmaceutical packaging by headspace gas chromatography was systematically analyzed. The sources of the uncertainty were analyzed for whole measurement procedure. Every uncertainty component was evaluated and quantified. The combined standard uncertainty and the expanded uncertain- ty were expressed. The result of the measurement of VCM in PVC sheet for solid pharmaceutical packaging was expressed as （4.17±0.18）×10^-7,k=2.