广州市2008年人群麻疹抗体水平监测分析

Analysis of Measles Antibody Among Population in Guangzhou in 2008

目的全面了解和掌握广州市各区、县级市人群麻疹抗体水平,为实施有效的控制预防及消除麻疹提供科学依据。方法2008年在广州市12个区、县级市中随机抽取9个区、县级市,采集孕妇、新生儿及0岁以上11个年龄组的健康人群静脉血各40人份,采用酶标ELISA法检测麻疹IgG抗体。结果调查4043名健康者,其中抗体阳性2856人,阳性率为70.64%。所调查的9个区(县级市)中,不同区(县级市)之间的麻疹抗体阳性率差别有统计学意义(χ2=400.313,P<0.05);12岁以上组则明显下降,各年龄组之间抗体阳性率差别有统计学意义(χ2=267.832,P<0.05)。结论应加强计划免疫工作,使整个人群的免疫水平达到一个稳定的水平;在一定年龄组加强免疫接种是进一步控制麻疹爆发和流行的有效措施。

Objective To determine the level of measles antibody in the population in Guangzhou and to provide scientific evidence of measles prevention and control. Method 40 serum samples from pregnant women, newborn and healthy individuals （0-20 years old） in 9 districts in Guangzhou were collected for the analysis of measles IgG antibody by the ELISA method. Result The sero-positive rate of measles was 70.39% （2810/4043）. The sero-positive rate in Conghua was significantly lower than the other districts （X2=400.313,P〈0.05）. The seropositive rate was increased significantly （X2=267.832,P〈0.05） in children over 12 years old. Conclusion Higher level of measles antibody was found in the people living in Guangzhou.Enhaneement of measles vaccination program is required for the disease control and prevention.