羧甲基壳聚糖钙的制备及其性质结构分析(英文)

Preparation and properties of carboxymethyl chitosan calcium

背景:羧甲基壳聚糖是壳聚糖改性得到的水溶性衍生物,具有多种生物活性,是金属离子的良好配体,可以与Ca2+进行络合配制一种新型生物材料。目的:研究羧甲基壳聚糖钙盐的制备方法,并对其性质结构进行分析。方法:羧甲基壳聚糖与氯化钙溶液反应生成羧甲基壳聚糖与钙的配合物,进行溶解度、羧甲基化度、旋转黏度、钙含量的测定,以及红外光谱、紫外光谱分析。结果与结论:配合物钙含量在15%左右,与羧甲基壳聚糖相比其溶解度、红外光谱和紫外光谱都产生了改变。制备出的羧甲基壳聚糖与Ca2+的配合物,通过一系列性质结构分析,初步证明为一种新型含钙化合物。

BACKGROUND：Carboxymethyl chitosan is a water-soluble derivate modified from chitosan,with various biological activities.It is a good ligand of metal ion and can integrate Ca2＋to prepare a novel biological material.OBJECTIVE：To explore a method for preparing carboxymethyl chitosan calcium（CCC）and analyze its properties and structure.METHODS：CCC was produced by carboxymethyl chitosan reacting with solution of calcium chloride.The solubility,carboxymethylation degree,rotational viscosity,and calcium content of CCC were determined,and infrared and ultraviolet spectral analyses were performed.RESULTS AND CONCLUSION：The calcium content of CCC was approximately 15%.Compared with carboxymethyl chitosan,infrared spectrum and ultraviolet spectrum of CCC were changed.The prepared CCC is a new calcium compound through property and structural analysis.