丹芪活肝胶囊对慢性乙型肝炎患者保肝及活血化瘀作用

Effects of Danqi Huogan Capsule in protecting the liver,promoting circulation and removing clots in patients with chronic hepatitis B

目的观察丹芪活肝胶囊对慢性乙型肝炎患者的保肝及活血化瘀作用。方法将104例慢性乙型肝炎患者随机分为治疗组和对照组,对照组(50例)采用常规护肝治疗,治疗组(54例)在常规治疗基础上加用丹芪活肝胶囊,重点观察治疗3个月前后两组患者临床症状、体征、肝功能,同时观察血液流变学的变化。结果治疗组患者治疗后临床症状、体征、肝功能明显好转(P<0.01),临床疗效好,并能明显降低红细胞压积、全血低切粘度、血浆粘度、红细胞聚集指数(P<0.05)。结论丹芪活肝胶囊对慢性乙型肝炎具有较好保肝及改善患者的血液流变性,具有活血化瘀的疗效。

Objective To assess the effect of Danqi Huogan Capsule in protecting the liver,promoting the circulation and removing blood clots in patients with chronic hepatitis B（CHB）.Methods A total of 104 CHB patients were randomized into two groups.Routine therapies for liver protection were given in the control group（n=50）,and Danqi Huogan Capsule was administered in the therapeutic group（n=54） in addition to the routine therapies.The changes in the clinical symptoms,physical signs,liver functions,and hemorrheology were observed after the 3-month therapies.Results Danqi Huogan Capsule treatment obvious improved the clinical symptoms,physical signs and liver functions of the patients（P〈0.01）,and significantly decreased the hematocrit,low-shear blood viscosity,plasma viscosity and index of red blood cell aggregation（P〈0.05）.Conclusion Danqi Huogan Capsule is effective in protecting the liver,improving hemorrheology,promoting the blood circulation and removing clots in patients with chronic hepatitis B.