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自体角膜缘干细胞联合羊膜移植治疗陈旧性眼部化学伤的疗效观察 被引量:6

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摘要 目的探讨自体角膜缘干细胞联合羊膜移植治疗陈旧性眼部化学伤的临床疗效。方法对陈旧性眼部化学伤(伤后大于3月)后持续性角膜上皮缺损及角膜溃疡30例(30眼),采用自体角膜缘干细胞联合人羊膜移植术进行治疗,并随访观察8周。结果28眼原上皮缺损区恢复光滑透亮,角膜溃疡全部或部分修复,治愈率达93.3%。结论角膜缘干细胞为病灶角膜提供了健康干细胞来源,恢复了眼表屏障功能;人羊膜本身无抗原性,且具有抗炎及抗纤维化作用,使其成为角膜上皮移行及生长的支架。自体角膜缘干细胞联合羊膜移植是一种有效的治疗陈旧性眼化学烧伤的手段。
作者 王军 尹东明
出处 《南方医科大学学报》 CAS CSCD 北大核心 2010年第3期657-658,共2页 Journal of Southern Medical University
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