心率变异非线性分析评估血管性痴呆患者心脏自主神经功能

Using Heartrate Variability non-line Analysis to Evaluate Cardiac Autonomic Nerve Function of Vascular Dementia Patients

目的:应用心率变异非线性分析评估血管性痴呆患者心脏自主神经功能损害情况。方法:应用动态心电图对124例血管性痴呆患者和102例对照病例进行24h监测,以Poincare散点图进行心率变异性(HRV)非线性分析,并比较两组定量指标矢量角度指数(VAI)及矢量长度指数(VLI)。结果:血管性痴呆组VAI(0.54±0.14)低于对照组(0.67±0.13),血管性痴呆组VLI(154.10+18.91)低于对照组(193.62±25.20),差异均有显著统计学意义(P<0.01);Poincare标绘散点图形状呈彗星状者血管性痴呆组50.8%(63例),对照组93.1%(95例),呈鱼雷状者血管性痴呆组患者31.5%(39例),对照组2.9%(3例),差异均有显著统计学意义(P<0.01)。结论:HRV非线性分析可作为无创伤性定量评价血管性痴呆患者心脏自主神经功能的可靠方法,有必要对痴呆患者的进行HRV检查,评估患者的自主神经功能状态。

Objective： Using heartrate variability non-line analysis to evaluate Cardiac autonomic nerve function of vascular dementia patients. Methods：Utilize holler to investigate 124 patients of vascular dementiame and 102 control subjects Using Poincare Scatter plot to analysis heartrate variability non.line, vector angle index（VAI） and vector length index（VLI） were analyzed. Results：The VAI of vascular dementia was significantly lower compare with control subjects （0.54±0.14 vs 0.67±0.13） and the VLI of vascular dementia was significantly lower compare with control subjects too（154. 10±18.91 vs 193.6±25.20 ）. Comet Poincare Scatter plot of vascular dementia was lower than control subjects（P〈0 01 ）. Conelusion：Heartrate variability non-line analysis may be benefit to evaluate Cardiac autonomic nerve function of vascular dementia patients.