凝血三项与血小板的联合检测对肝硬化患者的应用价值分析

Hemoglutination Three Items with Blood Platelet Union Examination to Liver Cirrhosis Patient's Application Value Analysis

目的:为了解肝硬化患者血浆凝血因子和血小板参数的变化,并探讨其临床应用价值。方法:应用日本sysmex CA-1500血凝仪和sysmexs SE-9000血细胞分析仪,对52例肝硬化患者和45例健康者凝血酶原时间(PT)、部分活化凝血酶时间(APTT)、纤维蛋白原(FIB)、血小板计数(PLT)及平均血小板体积(MPV)进行检测。结果:肝硬化患者PLT、MPV明显降低,与对照组的差异有显著性统计学意义(P<0.01);PT、APTT时间延长,FIB减低,与健康组对比,差异有显著性统计学意义(P<0.01)。结论:凝血三项与血小板的联合检测可从多方面客观准确地评价肝硬化患者凝血功能状况及其病情预后。

Objective：To understand the patients with liver cirrhosis plasma coagulation factor and platelet-parameter clanges,and to investigate its clinical value,Methods＇Japanese sysmex CA-1500 coagulation analyzer and sysmexs SE-9000 hematology analyzer, detected in 52 patients with liver cirrhosis and 45 healthy persons.ResultszThe patients with liver cirrhosis platetet count（PLT）,mean platelet volume （MPV） significantly reduced.and the control group there was significant difference（P〈0.01）;prothrombin time （PT）,part of the activated thromboplastin time （APTT） time extension, fibrinogen （FIB） reduced compared with the healthy group,there in a significant difference （P〈0.01）.Conelusion： The blood coagulation and platelet combined detection of three things from many different objective and accurate assessment of functional status of blood coagulation in patients with cirrhosis and its prognosis.