早期微量喂养联合益生菌预防早产儿坏死性小肠结肠炎

Early mininal feeding combined with probiotics to prevent necrotizing enterocolitis in preterm infant

目的探讨早期微量喂养联合益生菌培菲康预防早产儿坏死性小肠结肠炎发生的有效性。方法125例早产儿随机分为对照组(n=62)及治疗组(n=63),对照组给予微量喂养,治疗组在微量喂养的基础上加用益生菌,观察治疗期间两组发生坏死性小肠结肠炎(NEC)的情况。结果对照组62例,发生NEC9例,治疗组63例,发生NEC2例。结论早产儿早期微量喂养可减少NEC的发生,补充益生菌能降低早产儿的NEC发生率及NEC的病情,两者联合可起到协同作用。

Objective To explore the effectiveness which occurred in feeding microamount joint probiotics（Bifid Lriple Viable）in early to prevent necrotizing enterocolitis in premature infant.Methods 125 premature infant were randomly divided into controll group（n = 62）and the treatment group（n = 63）,controll group was given micro-feeding,the treatment group was added probiotics on the basis of the micro-feeding.Observing the situation of occurring necrotizing enterocolitis（NEC）which occurred in the two groups during treatment.Results In the controll group,there were 9 cases occurred NEC in the 62 cases 9;in the treatment group,there were 2 cases occurred NEC in the 63 cases.Conclusion The early micro-feeding in preterm infant can reduce the incidence of NEC,supplement of probiotics can reduce the incidence of NEC in preterm infant and the NEC＇s condition,it can play a synergistic frunction of combinating the two methords.