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11例牙源性钙化上皮瘤临床和病理分析 被引量:1

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摘要 目的探讨牙源性钙化上皮瘤临床和病理特点。方法选择本院2000年4月至2009年4月11例牙源性钙化上皮瘤,对其临床特点和病理特点进行分析。结果①临床表现:11例患者均有无痛性肿块,肿块表现为渐进性增大。8例骨内型患者有颌骨的局部膨胀;3例骨外型的患者有牙瘤样症状。②病理特点:骨外型病变为实质性的肿块,切面呈现灰白色;骨内型表现为局部颌骨膨胀性肿大,肿物的切面多数为实质性,切面表现为灰白色或者灰黄色。在光镜下,肿瘤的变异较大,主要有4种表现:肿瘤有多边形上皮细胞排列,成为大片状或者巢状,细胞间桥明显,细胞与胞核的多形性表现明显;肿瘤的上皮细胞排列成筛孔状,孔内有淀粉样物质;肿瘤的上皮细胞在粘液变现的间质内散在分布;瘤细胞为多边形且嗜伊红,还有胞浆透明的瘤细胞,这两种细胞排列为条索状。以一种为主要表现形式,在本组病例中,2例为第一种形式为主,4例以第二种形式为主,1例以第三种形式为主,4例以第四种形式为主。结论牙源性钙化上皮瘤有骨内型和骨外型两种,肿瘤的组织变异较大,可向局部侵袭性生长。在诊断中易被诊断为纤维性增生或者牙龈瘤等,在临床诊断中要防止误诊。
机构地区 南阳市口腔医院
出处 《中国现代药物应用》 2010年第6期150-151,共2页 Chinese Journal of Modern Drug Application
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