摘要
目的了解深圳市人民医院重症监护病房(ICU)革兰阴性杆菌的分布及其耐药性,指导临床合理用药。方法收集来自重症监护病房各类标本分离的革兰阴性杆菌540株,用VITEK AMS-60或VITEK-Ⅱ全自动微生物分析仪进行菌种鉴定,用K-B法进行药敏试验。结果ICU检出的革兰阴性杆菌以鲍曼不动杆菌、大肠埃希菌、铜绿假单胞菌和肺炎克雷伯菌为主,ESBLs阳性的大肠埃希菌和肺炎克雷伯菌比例为61.6%和51.8%,各类细菌对常用抗菌药物表现为严重耐药和多重耐药。结论该院ICU检出的革兰阴性杆菌以鲍曼不动杆菌、大肠埃希菌、铜绿假单胞菌和肺炎克雷伯菌为主,且呈现多重耐药性。
Objective To understand the distribution and antibiotic resistance among gram negative bacilli from intensive care unit(ICU) in Shenzhen People'S Hospital. Method 540 strains isolated from ICU were collected, which had been identified by VITEK AMS-60 or VITEK-Ⅱ system. K-B test was used for their antibiotic resistance. Result These bacillus consisted mainly of Baumanii, E. coli,Pseudomonas aeruginosa and K. pneumoniae. The detection rates of ESBLs for E. coli and K. pneumoniae were 61.6% and 51.8%, respectively. Most of these bacilli showed muhiantibiotic resist- ance. Conclusion Isolates from ICU are commonly mnltiantibiotic resistant;regular monitoring mechanism for antibiotic resistance should be established.
出处
《中国微生态学杂志》
CAS
CSCD
2010年第3期267-269,共3页
Chinese Journal of Microecology
关键词
ICU
革兰阴性杆菌
耐药性
ICU
Gram negative bacilli
Antibiotic resistance