期刊文献+

重症监护病房革兰阴性杆菌耐药性分析 被引量:12

Antibiotic resistance among gram negative bacilli in an intensive care unit
原文传递
导出
摘要 目的了解深圳市人民医院重症监护病房(ICU)革兰阴性杆菌的分布及其耐药性,指导临床合理用药。方法收集来自重症监护病房各类标本分离的革兰阴性杆菌540株,用VITEK AMS-60或VITEK-Ⅱ全自动微生物分析仪进行菌种鉴定,用K-B法进行药敏试验。结果ICU检出的革兰阴性杆菌以鲍曼不动杆菌、大肠埃希菌、铜绿假单胞菌和肺炎克雷伯菌为主,ESBLs阳性的大肠埃希菌和肺炎克雷伯菌比例为61.6%和51.8%,各类细菌对常用抗菌药物表现为严重耐药和多重耐药。结论该院ICU检出的革兰阴性杆菌以鲍曼不动杆菌、大肠埃希菌、铜绿假单胞菌和肺炎克雷伯菌为主,且呈现多重耐药性。 Objective To understand the distribution and antibiotic resistance among gram negative bacilli from intensive care unit(ICU) in Shenzhen People'S Hospital. Method 540 strains isolated from ICU were collected, which had been identified by VITEK AMS-60 or VITEK-Ⅱ system. K-B test was used for their antibiotic resistance. Result These bacillus consisted mainly of Baumanii, E. coli,Pseudomonas aeruginosa and K. pneumoniae. The detection rates of ESBLs for E. coli and K. pneumoniae were 61.6% and 51.8%, respectively. Most of these bacilli showed muhiantibiotic resist- ance. Conclusion Isolates from ICU are commonly mnltiantibiotic resistant;regular monitoring mechanism for antibiotic resistance should be established.
出处 《中国微生态学杂志》 CAS CSCD 2010年第3期267-269,共3页 Chinese Journal of Microecology
关键词 ICU 革兰阴性杆菌 耐药性 ICU Gram negative bacilli Antibiotic resistance
  • 相关文献

参考文献6

二级参考文献52

  • 1朱德妹,汪复,胡付品,吴湜,张婴元.2002年上海地区医院细菌耐药性监测[J].中华传染病杂志,2004,22(3):154-159. 被引量:63
  • 2应文娟,王佩芬,余雪涛.ICU院内分离菌菌谱及其耐药特性分析[J].现代护理,2004,10(8):697-699. 被引量:1
  • 3熊自忠,朱德妹,汪复,张婴元.CTX-M-14和CTX-M-24编码基因的检测及其功能表达[J].中华医学杂志,2004,84(17):1454-1459. 被引量:15
  • 4佟训靓,李明成.铜绿假单胞菌多重耐药性分子机制的研究[J].北华大学学报(自然科学版),2006,7(1):31-34. 被引量:6
  • 5Bergogne-Berezin E.Guideline on antimicrobial chemotherapy for prevention and treatment of infections in the ICU[J].J Chemother,2001,1(1):134-149.
  • 6Murray PR,Barom EJ,Pfaller MA,et al.Manual of clinical laboratory[M].7th Edition.Washington DC:American Society for Microbiology,1999:552-554.
  • 7Bush K,Jacoy HA,Medeiros AA.A Functional Classification S-cheme for Beta-lactamasess and Its Correlation with Molecular Structure[J].Antimicrob Agents Chemother,1995,39:1211-1233.
  • 8Li Y,Mima T,Komori Y,et al.A new member of the tripartite multidrug efflux pumps,MexV-W-OprM,in Pseudomonas aeruginosa.J Antimicrob Chemother,2003,52:572-575.
  • 9Lynch MJ,Drusano GL,Mobley HLT.Emergency of resistance to imipenem in Pseudomonas aeruginosa.Antimicrob Agents Chemother,1987,31:1892-1896.
  • 10Hyunjoo P,Jong-Won K,Jungmin K,et al.Carbapenem resistance mechanisms in Pseudomonas aeruginosa clinical isolates.Antimicrob Agents Chemother,2001,45:480-484.

共引文献431

同被引文献58

引证文献12

二级引证文献68

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部