肠球菌属医院感染临床分析和耐药性研究

Clinical analysis and drug resistant study of nosocomial infection of Enterococci

目的:调查我院住院肠球菌属感染患者临床感染情况及耐药性研究,为临床诊断和治疗提供准确可靠的依据。方法:回顾性分析2005年2月至2008年3月分离出肠球菌属住院患者的临床资料和耐药性情况。结果:氨苄西林和青霉素对粪肠球菌敏感性为46.31%和45.37%,对屎肠球菌的药物敏感性均为46.05%。粪肠球菌和屎肠球菌对万古霉素的敏感性分别为90.18%和90.55%。结论:肠球菌属细菌耐药情况日趋严重,万古霉素抗菌活性最强,及时合理地治疗是控制病情的关键。

Objective：To investigate the information about the present nosocomial infection characteristics and drug resistance of Enterococci to provide accurate and reliable basis for clinic.Methods：The clincial data of nosocomial infection by Enterococci and the drug resistance were retrospectively analyzed from Feb.2005 to Mar.2008.Results：Ampicillin and penicillin were susceptible against E.faecalis,inhibition rates being 46.31% and 45.37%,respectively.Strains of E.faecium accounted for 46.05%.The sensitive rate of E.faecalis and E.faecium to vancomycin was 90.18% and 90.55%,respectively.Conclusion：The resistance of the clincial isolated of Enterococci is severe gradually and vancomycin has the best antibacterial capacity against Enterococci.Early diagnosis and rational treatment are the key to cure these patients.