早期机械通气对急性重症左心衰竭患者病死率的影响

Effect of Early Mechanical Ventilation on Mortality of Patients With Severe Acute Left Ventricular Failure

目的:研究早期机械通气对急性重症左心衰竭患者病死率的影响。方法:急性重症左心衰竭患者9例,随机分为早期机械通气组(n=45)和常规机械通气组(n=45),观察症状缓解时间、机械通气时间、7d病死率的差别。结果:两组患者在症状缓解时间上(4.7±1.7hvs5.0±1.8h,P>0.05);在机械通气时间上,早期机械通气组显著低于常规机械通气组(15.6±4.5hvs33.1±13.4h,P<0.01);早期机械通气组第7天病死率也显著低于常规机械通气组(8.9%vs26.7%,P<0.05)。结论:早期机械通气可降低急性重症左心衰竭患者病死率。

Objective：To investigate the effect of early mechanical ventilation on mortality of patients with severe acute left ventricular failure.Methods：Ninety patients with acute left ventricular failure were divided into early mechanical ventilation group （n=45） and conventional mechanical ventilation group （n=45）.Time of symptomatic relief,duration of mechanical ventilation and the mortality on 7 days were observed.Results：There was no difference in time of symptomatic relief between the two groups （4.7±1.7h vs 5.0±1.8h,P0.05）;but the duration of mechanical ventilation was significantly shorter in the early mechanical ventilation group than that in conventional mechanical ventilation group （15.6±4.5h vs 33.1±13.4h,P0.01）;and the mortality on 7 days was significantly lower than that in conventional mechanical ventilation group （8.9% vs 26.7%,P0.05）.Conclusion：Early mechanical ventilation can decrease the mortality of patients with severe acute left ventricular failure.