冠心病合并脑梗塞患者外周动脉硬化与冠状动脉硬化的相关性研究

The Correlation Study on Peripheral Arterial Atherosclerosis and Coronary Atherosclerosis in Coronary Artery Disease with Cerebral Infarction

目的:观察冠心病合并脑梗塞患者颈动脉(CA)、股动脉(FA)、股浅动脉(SFA)、胭动脉(PA)内-中膜厚度(IMT)与冠状动脉硬化的相关性。方法:选经冠状动脉造影确诊为冠状动脉疾病(CAD)的患者36例,选冠状动脉照造证实无冠状动脉狭窄的患者20例为对照组,采用二维超声检测颈、股、股浅月、国动脉IMT。动脉粥样硬化斑块积分采用Sutton法,并与冠状动脉病变程度进行对比分析。结果:冠心病合并脑梗塞患者IMT,斑块积分显著高于对照组(P<0.001)。斑块指数与冠状动脉病变程度呈正相关。结论:冠心病合并脑梗塞患者颈、股、股浅、月国动脉粥样硬化与冠状动脉粥样硬化的病变相平行。

Objective：To investigate the Intimate media Thickness（IMT） of carotid artery（CA）,Femoral artery（FA）,Superficial Femoral artery（SFA）,popliteal artery（PA）and coronary atherosclerosis with coronary artery disease （CAD）and cerebral infarction（CI）.Method： Two-dimens ional echocardiography（2-DE）was used to measure the IMT and plague of CA,FA,SFA,PA with 36 CAD and CI patients who had been examined by coronary angiography and CT or MRI.CA,FA,SFA,PA Plaque score was calculated using Suttons method to quantify the extent of CA,FA,SFA,PA atheroasclerosis.The carotid,femoral,superficial semoral,popliteal artery atherosclerosis and coronary atherosclerosis.of CAD and CI were analyzed and compared.And 20 persons who had been examined by coronary angiography and CT or MRI were healthy for control group.Result： The IMT and P1aque score of carotid,femoral,superficial femoral,popliteal artery weres significantly increased in CAD and CI group than in control group.Conclusion：Carotid,femoral,superficial femoral.popliteal artery atheroasclerosis and coronary atheroasclerosis are parallel in CAD and CI.