硬膜外腔注入丁丙诺啡辅助全麻用于开胸手术效果观察

The Effects Observation of the Epidural Injected With Buprenorphine Assist General Anesthesia for Chest Surgery

将２１例ＡＳＡⅠ－Ⅱ普胸手术病人随机分为二组，慢诱导气管插管后，组Ⅰ术前２０ｍｉｎ经硬膜外导管一次注入丁丙诺啡６μｇ／ｋｇ，组Ⅱ术前静注芬太尼。两组均以１％普鲁卡因＋司可林，间断静注芬太尼维持。观察切皮后血压、心率变化及术中芬太尼总量，术后止痛药用量。结果：组Ⅰ、组Ⅱ麻醉时间无差异（Ｐ＞０．０５）；芬太尼用量组Ⅰ明显少于组Ⅱ（Ｐ＜０．０１）；组Ⅰ及组Ⅱ间血压无明显差异（Ｐ＞０．０５）。术后镇痛效果组Ⅰ明显优于组Ⅱ。提示硬膜外腔注入丁丙诺啡复合浅全麻是一种安全。

In order to observe the effects of epidural being injected with buprenorphine during anesthesia and operative trauma,twenty-one ASA grade Ⅰ-Ⅱ patients were randomly divided into two groups.After low dose of narcotics for endotracheal intubation,Group I,the epidural,was injected with buprenorphine 5-6 μg/kg 20 min before operation.Group Ⅱ was injected with fentanyl.1% procaine was used combining with scoline and fentanyl maintaine anesthesia in both groups.The each patient Bp.HR was observed careful before and after skin incision.The amount of fentanyl used during operative trauma and drugs used for postoperative analgesia were also observed.The results showed that the time of anesthesia had no significant difference between two groups( P >0.05).In Group I,the total dose of fentanyl used were lower than Group Ⅱ( P < 0.01 ).Blood pressure had no significant difference between two groups and Group I( P >0.05).