期刊文献+

缺血性脑卒中颅内动脉狭窄的危险因素分析 被引量:20

下载PDF
导出
摘要 目的探讨缺血性脑卒中患者颅内动脉狭窄的危险因素,为缺血性脑卒中的病因诊断、治疗和预防提供重要依据。方法90例缺血性脑卒中患者根据全脑血管造影术检查(DSA)结果,分为对照组(狭窄<50%)与颅内动脉狭窄组(狭窄>50%或闭塞),分析颅内动脉狭窄与年龄、性别等相关危险因素的关系。结果缺血性脑卒中患者颅内动脉狭窄组与对照组的高血压、糖尿病、冠心病和血浆HDL-C、血清脂蛋白Lpa比较差异有统计学意义(P<0.05),而年龄、性别、吸烟、既往卒中史、脑血管病家族史、CHO、TG、LDL-C、ApoA、ApoB两组间比较差异无统计学意义(P>0.05)。结论高血压、糖尿病、冠心病、血清脂蛋白Lpa可能为缺血性脑卒中患者颅内动脉狭窄的危险因素,HDL-C为颅内动脉狭窄的保护因素。
作者 邓晓 秦超
出处 《广西医学》 CAS 2010年第1期50-52,共3页 Guangxi Medical Journal
  • 相关文献

参考文献12

  • 1Wong KS,Huang YN,Gao S,et al.Intracranial stenosis in Chinese patients with acute stroke[J].Neurology,1998,50(3):812-813.
  • 2Huang YN,Gao S,Li SW,et al.Vascular lesion in Chinese transient ischemic attacks[J].Neurology,1997,48(2):524-525.
  • 3Larry BG,Robert A,Kyra B,et al.Primary prevention of ischemic stroke.A statement for health care professionals from the stroke.Council of American Heart Association[J].Sroke,2001,32(1):280-299.
  • 4Mendes I,Baptista P,Soares F,et al.Diabetes mellitus and intracranial stenosis[J].Rev Neurol,1999,28(11):1 030-1 033.
  • 5Selvin E,Marinopoulos S,Berkenblit G,et al.Meta-analysis:glycosylated hemoglobin and cardiovascular disease in diabetes mellitus[J].Ann Intern Med,2004,141(6):421-431.
  • 6Tanne D,Koren-Morag N,Goldbourt U.Fasting plasma glucose and risk of incident ischemic stroke or transient ischemic attacks:a prospective cohort study[J].Stroke,2004,35(10):2 351-2 355.
  • 7王洪新,韩仲岩.高血压、糖尿病与进展性脑卒中的相关研究[J].卒中与神经疾病,2002,9(6):364-365. 被引量:64
  • 8Hennes MM,O'Shaughnessy IM,Kelly TM,et al.Insulin-resistant lipolysis in abdominally obese hypertensive individuals[J].Hypertension,1996,28(1):120-126.
  • 9Wong KS,Huang YN,Gao S,et al.Intracranial stenosis in Chinese patients with acute stroke[J].Neurology,1998, 50(3):812-813.
  • 10Amarenco P,Labreuche J,Touboul PJ.High-density lipoprotein-cholesterol and risk of stroke and carotid atherosclerosis:a systematic review[J].Atherosclerosis,2008,196(2):489-496.

二级参考文献12

  • 1中华医学会神经病学分会.急性缺血性脑卒中患者处理建议(1998)[J].中华神经科杂志,1998,10(30):305-306.
  • 2项志敏,中华心血管病杂志,1994年,3期,195页
  • 3Wu J H,Clin Chem,1993年,39卷,209页
  • 4Carberg B, Asplund K, Hagge E. Factors influencing admission blood pressure levels in acute stroke. Stroke, 1991, 22(4):527
  • 5Philips SJ. Pathophysiology and management of hypertension in acute ischemic stroke. Hypertension, 1994, 23 ( 1 ): 131
  • 6Ceriello A, Falleti E, Bortolotti N, et al. Increased circulating intercellular adhesion molecule-lexpression in cultured human vascular endothelial cells. Cells J clin Invest, 1994, 98:885
  • 7Mcleod Ds, Lefer DJ, Merges C, et al. Enhanced expression of ihtercellular adhesion molecule-land P-selectin in the diabetic human retina and chroid. AM J Pathol, 1995, 147:642
  • 8Linn T, Stmate C, Federlin K, et al. Intercellular adhesion molecule-1, expression in the islets of nonobese diabetes and lowdosestretozocin-treated mouse. Histochemistry, 1994, 102:317
  • 9Herold K, Vezys V, Gage A, et al. Prevention of autoimmune diabetes by treatment with anti-LFA-1 and anti-ICAM-1 monoclonal antibody. Cell Immunoi, 1994, 157:489
  • 10Matsui H, Suzuki M, Tsukuda R, ET al. expression of ICAM-1 on glumeruli isassociated with pyogression of diabetic nephropathy in a genetically obese diabetic rats wister fatty. Diabetes Res clin pract,1996, 32(1-2):1

共引文献65

同被引文献184

引证文献20

二级引证文献154

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部