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前列腺增生患者经尿道等离子体双极电切术后血清前列腺特异性抗原的变化 被引量:2

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摘要 目的:观察经尿道等离子体双极电切术(PKRP)对前列腺增生(BPH)患者血清中的总前列腺特异性抗原(t-PSA)和游离/总前列腺特异性抗原(f/tPSA)比值的影响,探讨其在PKRP术后随访中的意义。方法:对90例BPH患者行PKRP治疗,采用化学发光免疫法分别检测术前、术后24h及术后1、2、6个月患者血清中的t-PSA和f-PSA水平,并计算f/tPSA比值,随访比较分析手术前后PSA变化差异。结果:术后24h患者血清t-PSA值平均为(15.5±7.6)ng/mL,明显高于术前患者血清t-PSA值(6.2±5.5)ng/mL,差异有统计学意义(P<0.05)。术后1个月血清t-PSA值较术前明显降低,术后2个月降至最低,随后血清t-PSA趋于稳定;血清f/tPSA比值术前术后任何时段比较差异均无统计学意义(P>0.05)。结论:PKRP可显著降低BPH患者血清中的PSA,术后2个月PSA稳定至最低水平;与血清中的t-PSA和f-PSA水平相比,血清f/tPSA比值是PKRP术后短期及长期随访的一个更可靠指标。
出处 《实用医学杂志》 CAS 北大核心 2010年第5期775-776,共2页 The Journal of Practical Medicine
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参考文献6

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共引文献266

同被引文献18

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