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帕金森病脑MRI研究进展 被引量：1

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摘要 帕金森病（Parkinson disease，PD）是一种常见的神经退仃性疾病，主要累及运动系统，临床上的三大特征性表现为静止性震颤、肌强直及运动迟缓。此外，PD也累及感觉、认知等多个系统，导致感觉减退、抑郁、痴呆等症状。PD的主芟病理表现为黑质纹状体多巴胺神经元减少、丢失和残存神经元中Lewy小体生成。
作者 曹恒毅 张敏鸣
机构地区 浙江大学医学院附属第一医院放射科
出处 《中华放射学杂志》 CAS CSCD 北大核心 2010年第3期332-334,共3页 Chinese Journal of Radiology
关键词 帕金森病 黑质纹状体多巴胺神经元 脑MRI LEWY小体 运动系统 感觉减退 静止性震颤 运动迟缓
分类号 R742.5 [医药卫生—神经病学与精神病学]
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  • 1Damier P, Hirsch EC, Agid Y, et al. The substantia nigra of the human brain. I. Nigrosomes and the nigral matrix, a compartmental organization based on calbindin D(28K) immunohistochemistry[J].Brain, 1999, 122(Pt 8):1421-1436.
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  • 10高平,周佩洋,李光,王普清,刘焦枝,徐峰,武夏夏.3T磁敏感加权成像中非帕金森病者黑质“燕尾征”存在普遍性的分析[J].中山大学学报（医学科学版）,2015,36(4):635-640. 被引量：6

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中华放射学杂志
2010年 第3期

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