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Ca^2＋、calpain-2和AQP1在大鼠糖尿病性白内障晶状体中的变化及意义 被引量：2

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摘要 晶状体的透明依赖于晶状体蛋白质、水、电解质等的正常生理代谢，晶状体囊膜尤其是囊膜下上皮细胞的正常生理功能是维持晶状体透明的重要因素。糖尿病性白内障（diabeticcataract，DC）是糖尿病患者常见的眼部并发症，其病理变化主要是晶状体前、后囊膜下皮质纤维化和混浊，其发病的分子生物学机制至今仍不明确。
作者 张新芳 张虹 王芳 陈芳
机构地区 华中科技大学同济医学院附属同济医院眼科 中西医结合研究所
出处 《中华眼科杂志》 CAS CSCD 北大核心 2010年第2期171-175,共5页 Chinese Journal of Ophthalmology
关键词 糖尿病性白内障 白内障晶状体 CA^2+ AQP1 分子生物学机制 晶状体囊膜 大鼠 晶状体蛋白质
分类号 R587.1 [医药卫生—内分泌] R776.1 [医药卫生—眼科]
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参考文献14

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二级参考文献20

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共引文献22

同被引文献27

  • 1张虹,彭洁,胡维琨,谢二娟,李贵刚.透明晶状体和老年性白内障晶状体上皮细胞水通道蛋白1的表达[J].华中科技大学学报（医学版）,2004,33(3):360-362. 被引量：8
  • 2熊新春,苗娟,席祖莲,张海江,胡义珍,魏厚仁.地塞米松对体外培养的晶状体上皮细胞水通道蛋白-1表达的影响[J].眼科研究,2006,24(5):472-475. 被引量：3
  • 3张虹,张金玲.水通道蛋白在大鼠氧化性白内障晶状体上的表达[J].华中科技大学学报（医学版）,2007,36(3):374-376. 被引量：7
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  • 10Gonen T,Sliz P,Kistler J,et al.Aquaporin-0 membrane junctions reveal the structure of a closed water pore[J].Nature,2004,429(6988):193-197.

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二级引证文献4

中华眼科杂志
2010年 第2期

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