摘要
对1154例孕妇及丈夫作ABO、Rh(D)血型检查。有ABO血型不合者,测IgG抗A(B)抗体效价;Rh(D)阴性者,查IgG抗D抗体。又对其中204例产前有新生儿溶血病(HDN)危险的孕妇(即产前ABO不合,IgG抗A(B)≥64或有Rh抗体者),所生新生儿作血型及3项试验,以证实产前IgG抗体效价高低与HDN发病率的关系。结果:ABO系不合者占42%,妇夫血型不合检出率依次为OA>OB>OAB,效价≤64占755%,≥512占12%;Rh阴性检出率为138%,阴性产生抗D机率为525%,204例产前预报有HDN可能的孕妇中,有38例新生儿患有HDN,占186%。
The ABO,Rh(D) blood types were tested in 1 154 gravidas and their husbands,and IgG anti A(B) valence of antibody and IgG anti D antibodies were measured when ABO blood type was disagreement and Rh(D) negative,respectively.The blood type and three experiments were done in 204 gravidas who had risk of hemolytic disease of newborn (HDN) (ie.ABO disagreement,IgG anti A(B)≥64 or positive Rh antibodies),to determine the relation of valence of IgG antibody and disease incidence morbidity of HDN.The results showed that the disagreement rate in ABO series was 42%,in proper detection rates in wife and husband O A>O B>O AB order,valence(≤64) 75 5% and (≥512) 1.2%.Detection rate of negative Rh was 1.38%,and negative producing anti D probability 52.5%,and HDN of neonate(38 cases)18.6% in predictin possibility of HDN of 204 gravidas before birth.It is suggested that the magnitude of valence of IgG blood type antibody is directly proportional to incidence of HDN.
出处
《河南医科大学学报》
1998年第4期74-76,共3页
Journal of Henan Medical University
关键词
IGG抗体
新生儿溶血
溶血病
gravida
serum IgG anti A(B) antibody
serum IgG anti D antibody
HDN