中心性浆液性脉络膜视网膜病变荧光素眼底血管造影48例

Central serous chorioretinopathy fundus fluorescein angiography in 48 cases

目的:分析中心性浆液性脉络膜视网膜病变(central serous chorioretinopathy,CSC)的临床特征和荧光素眼底血管造影(fundus flurorescein angiography,FFA)特征。方法:对48例58眼CSC患者的视力、初诊年龄、双眼患病率、男女发病比例及FFA特征进行分析。结果:女CSC患病率比男低(1∶5.86);≤45岁的CSC患者30例35眼,其中双眼发病5例,FFA单灶渗漏17眼(48.6%),多灶渗漏9眼(25.7%),不典型渗漏9眼(25.7%);>45岁CSC患者18例23眼,其中双眼发病5例,FFA单灶渗漏2眼(8.7%),多灶渗漏11眼(47.8%),不典型渗漏10眼(43.5%)。两组比较具有非常显著差异(P<0.01)。结论:≤45岁FFA表现单灶渗漏及墨渍、喷出型渗漏。>45岁FFA灶型渗漏及色素上皮失代偿,双眼发病较年轻患者多见,复发者渗漏点多靠近原发灶。

AIM： To analyze the clinical characteristics and fundus fluorescein angiography （FFA） characteristics of the central serous chorioretinopathy （CSC）. METHODS： Visual acuity, age of first treatment, prevalence of both eyes, male and female incidence ratio and FFA features of 48 CSC patients （58 eyes） were analyzed. RESULTS： CSC prevalence of female was lower than that of male （1 ： 5.86） ; There were 30 CSC patients （35 eyes） ≤ 45-year-old, with 5 cases of both eyes. FFA single leakage was in 17 eyes （48. 6%）, multi-lesion leakage in 9 eyes （25, 7%）, atypical leakage in 9 eyes （25.7%）; 18 CSC patients（23 eyes） were more than 45- year-old with 5 cases of both eyes. FFA single lesion leakage was in 2 eyes （8.7%）, multi-lesion leakage in 11 eyes （47.8%）, atypical leakage in 10 eyes （43.5%）. The comparison between the two groups had significant differences （P〈0. 01）. CONCLUSION： ≤ 45-year-old FFA performed a single lesion leakage and ink stains, spray-type leakage. 〉 45- year-old FFA leakage and pigment epithelium-type lesions decompensation of both eyes were more common than younger patients , leakage in recurrence was near the original point.