摘要
肿瘤坏死因子样弱凋亡诱导因子(TWEAK)是肿瘤坏死因子配体超家族的新成员,按被发现的时间先后称为第十二成员(TNFSF12),现发现其具有广泛的生物学活性,在多个系统的疾病发病机制中起着重要作用。
TWEAK(TNF-like weak inducer of apoptosis), is a novel member of the TNF superfamilies, also known as TNFSF12 (TNF-superfamily member 12). TWEAK is a muhifunctional cytokine which has extrensive biological activities, plays a important role in pathogenesis of many diseases , especially in autoimmune diseases. In this review, we summarizes the advance of TWEAK in autoimmune diseases.
出处
《国际免疫学杂志》
CAS
北大核心
2010年第2期92-96,共5页
International Journal of Immunology
基金
国家自然科学基金资助项目(30972749)