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信号转导通路与糖尿病肾病的关系 被引量：1

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摘要 糖尿病是胰岛素分泌缺陷和（或）胰岛素作用障碍而导致的一组以高血糖为特征的慢性代谢性疾病。长期高血糖状态可以导致包括肾脏在内的多种组织器官的损伤和功能障碍。随着人民生活水平的不断提高，糖尿病发病率逐年上升。目前全球约有1．5亿糖尿病患者。我国约有3000万名糖尿病患者，而糖尿病的各种慢性并发症已成为糖尿病致残致死的主要病因。作为慢性并发症之一的糖尿病。肾病（DN）是糖尿病致残因素和重要的死亡原因之一。
作者 吴英 王力宁
机构地区 沈阳二四二医院肾脏内科 中国医科大学第一附属医院
出处 《临床内科杂志》 CAS 2010年第3期212-214,共3页 Journal of Clinical Internal Medicine
关键词 高血糖 活性氧 糖尿病肾病 酪氨酸激酶/信号转导子
分类号 R589.71 [医药卫生—内分泌]
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参考文献18

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共引文献25

同被引文献16

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临床内科杂志
2010年 第3期

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