血必净注射液治疗慢性肺源性心脏病失代偿期的临床疗效分析

Clinical efficacy analysis of Xuebijing injection in treatment of decompensated chronic pulmonary heart disease

目的研究血必净注射液对慢性肺源性心脏病（肺心病）失代偿期患者的临床疗效分析。方法将45例慢性肺心病失代偿期患者按就诊顺序随机分为治疗组23例和对照组22例，治疗组采用血必净注射液100ml加生理盐水250ml，静脉滴注2次／d，其余治疗2组相同，观察治疗前及治疗后14d2组的显效率、血气分析、临床平均住院时间等指标。结果治疗组临床症状的改善、血气分析指标的好转均优于对照组（P〈0．05），平均住院时间明显缩短[治疗组（10．8±2．4）d，对照组（14．0±3．2）d，P〈0．05]，总有效率91．3％（21／23），高于对照组（81．8％，18／22）。结论血必净注射液对慢性肺心病失代偿期有明显疗效。

Objective To study the effect of xuebijing injection in the treatment of decompensated chronic pulmonary heart disease. Methods Forty-five patients diagnosed with decompensated chronic pulmonary heart disease were divided into treatment group and control group randomly, 23 patients in treatment group and 22 in control group. In treatment group, the mixture of 100ml of xuebijing injection and 250 ml of mormal saline was administrated into patients with ivgtt, twice a day. The other drugs were same in both groups. Then observed the changes in the clinical symptoms, blood gas analysis and healing well time and so on. Results Compared with control group, clinical symptoms, the changes of blood gas analysis and average time of hospital stay were significantly improved. The rate of healing well was higher than that of control group. Conclusion Xuebijing injection has a significant positive effect in the treatment of decompensated chronic pulmonary heart disease.