双黄连注射液灌肠治疗婴幼儿手足口病162例

Clinic observation on retention enema of Shuanghuanglian Injection in treating 162 Cases of infant hand-foot-mouth disease

目的 观察双黄连注射液保留灌肠治疗婴幼儿手足口瘸的临床疗效。方法将162例婴幼儿手足口病患儿随机分为两组：治疗组81例采用双黄连注射液保留灌肠治疗，对照组81例给予利巴韦林颗粒治疗，观察、比较其临床疗效。结果治疗组和对照组的总有效率分别为97．53％和88．89％，两组总有效率比较，差异有统计学意义（X^2=5．872，P〈0．05）；治疗组的主要临床症状、体征缓解时间及病程明显优于对照组（P均〈0．05）。结论双黄连注射液保留灌肠治疗婴幼儿手足口病有疗。

Objective To observe the effects of retention enema of Shuanghuanglian injection in treating infantile hand-foot-and-mouth disease. Methods A total of 162 patients of hand-foot-mouth disease were recruited into a control group and treatment group randomly, with 81 cases in each group. The treatment group was treated with retention enema of Shuanghuanglian injection, and the control group was treated with ribavirin granules. Clinical effects were observed in both groups. Results The total effective rate of the treatment group and the control group was 97.53% and 88.89% respectively, showing statistical significance （P〈0.05）. The time of clinical symptom relief and course of treatment were shorter in the treatment group than those in the control group （P〈0.05）. Conclusion Retention enema of Shuanghuanglian injection is effective in treating infantile hand-foot-mouth disease.