应用HPLC法测定唐福康胶囊中的罗格列酮

Application of HPLC Determination Tang Fukang capsules rosiglitazone

目的建立液相色谱法测定唐福康胶囊中罗格列酮含量的方法。方法选用C18色谱柱,以0.01 mol/L醋酸胺(用冰醋酸调节pH值至3.5)-乙腈(45:55)为流动相,UV检测波长为230 nm。结果本方法的回收率为99.31%,RSD=0.9%(n=6)。结论该方法简便,准确,重现性好。

Objective To develop a HPLC method for the contents determination of Rosiglitazone intangfukang Capsules.Methods The C18 column was used with a mobile phase was 0.01 mol/L ammonium acetate solution（adjusted to pH=3.5 with acetic acid）-Acetonitrile（45：55）.The detection wavelength was 230nm.Results The average recovery was 99.31%（n=6）.Conclusion The method is simple,sensitive and accurate.