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GLP-1相关降糖药物的临床应用 被引量：7

Clinical progress of GLP-1 based therapy on diabetes
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摘要 胰高血糖素样肽-1（GLP-1）具备多重抗高血糖作用。近年来基于其治疗2型糖尿病的方案已成为新的研究热点并引起广泛关注。它的几种类似物作为新的降糖药物相继完成Ⅲ期临床研究并在一些国家上市。现就GLP-1的结构、功能，以及几种相关降糖药物的临床研究做一概述。 GLP-1 has muhiple effect on anti-hyperglycemia,thus the therapy based on GLP-1 in type 2 diabetes mellitus has been extensive reported. Accompanied with the completion of phase m study, GLP-Ⅰ analogues were lunched in some countries. This review focuses on the structure and functions of GLP-1, and the updated clinical development on the agents based on it.
作者 景国强 李彩萍
机构地区 内蒙古医学院附属医院内分泌科
出处 《国际内分泌代谢杂志》 2010年第2期94-96,共3页 International Journal of Endocrinology and Metabolism
关键词 胰高血糖素样肽-1 2型糖尿病 GLP-1类似物 二肽基肽酶-Ⅳ Glucagon-like peptide-1 Type 2 diabetes mellitus GLP-1 analogues Dipeptidyl-peptidase Ⅳ
分类号 R587.1 [医药卫生—内分泌]
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参考文献22

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二级参考文献18

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共引文献6

同被引文献80

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引证文献7

二级引证文献34

国际内分泌代谢杂志
2010年 第2期

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