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产后出血休克发生缺氧缺血性脑病临床分析 被引量:2

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摘要 目的探讨产后出血休克发生缺氧缺血性脑病的高危因素、发病机制、早期诊断及其防治措施。方法对203例产后出血休克发生缺氧缺血性脑病25例患者的临床资料进行回顾性分析。结果导致25例缺氧缺血性脑病的危险因素主要是羊水栓塞和重度子痫前期或子痫,且为Ⅲ~Ⅳ级休克、产后出血量〉1500ml者。脑电图轻度异常5例,中至重度异常5例。头颅CT示单侧或双侧基底节对称性低密度4例,大脑白质脱髓鞘病变6例,既有基底节对称性低密度又有大脑白质脱髓鞘病变5例。磁共振脑血管造影示双侧苍白球坏死3例,单侧苍白球坏死4例,脑自质广泛脱髓鞘11例,脑梗死3例,大脑中动脉闭塞4例。25例患者随访1年,痊愈16例,好转6例,无效1例,死亡2例。结论积极治疗羊水栓塞、妊娠期高血压疾病等原发病,控制诱因的进一步发展,尽早干预,纠正休克,缩短弥散性血管内凝血时间,及时发现缺氧缺血性脑病的征兆并积极治疗,给予预处理,是降低产后出血引起缺氧缺血性脑病的关键。
出处 《中国医师进修杂志》 2010年第9期46-48,共3页 Chinese Journal of Postgraduates of Medicine
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