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PAI-1及其在肾小球硬化中的作用及意义 被引量:8

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摘要 肾小球硬化是由各种原因所致的肾小球损伤或病变的共同结局。肾小球细胞外基质(extracularmatrix,ECM)积聚是引起肾小球硬化的重要病理基础。正常生理条件下,肾小球ECM的合成与降解呈现相对平衡状态,这对维持肾小球的正常结构和功能起着重要作...
作者 秦蓉
出处 《临床与实验病理学杂志》 CAS CSCD 1998年第6期579-581,共3页 Chinese Journal of Clinical and Experimental Pathology
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  • 1Mignatti P.Extracellular matrix remodeling by metalloproteinases and plasminogen activators.Kiddy Int,1995,47(suppl):S12-14.
  • 2Schnaper HW. Balance between matrix synthesis and degradation:a determinant of glomerulosclerosis. Pediatr Nephrol,1995,9(1):104-111.
  • 3Bosma PJ, Eva A, Van den Berg, Kooistra T, et al. Human plasminogen activator inhibitor-1 gene.J Biol Chem, 1998,263(19):9129-9141.
  • 4Bruzdzinski CJ, Johnson MR, Nordhy EC,et al.lsolation and characterization of the rat plasminogen activator inhibitor-1 gene.J Biol Chem,1990,265(4):2078-2085.
  • 5Simpson AJ,Booth NA,Moore NR,et al.Distribution of plasminogen activator inhibitpor (PAI-1)in tissue.Am J Pathol,1991,44:139-143.
  • 6Kutz SM, Nikey SAT, White LA, et al.Induced PAl-1 mRNA expression and targeted protein accumulation are early G1 events in serum-stimulated rat kidney cells, J Cell Physiol.1997,170:8-18.
  • 7Colucci M.Gsualdo L,Montemurro P,et al.Cultured humanmesangial cells produce both type I and type 2 plasminogen activator inhibitors.Thromb Haemost, 1995,74((6):1516-1520.
  • 8Lacava R,Rondeau E.Ochi S,et al.Characterization of a ptasminogen activator and its inhibitor in human mesangial cells. Kidney Int,1989,35,806-811.
  • 9Hagege J, Peraldi MN, Rondeau E, et al. Plasminogen activator inhibitor-1 deposition in the extracellular matrix of cultured human mesangial cells.Am J Pathol,1992,141(1):117-128.
  • 10Tomooka S, Border WA, Marshall BC, et al. Glomerular matrix accumulation is linked to inhibition of the plasmin protease system. Kidney Int,1992,42:1462-1469.

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