摘要
在心脏外科领域中,人工心脏瓣膜置换术是治疗心脏瓣膜性病变的主要外科治疗手段,然而,临床上可以使用的人工心脏瓣膜存在不同程度的缺陷。随着组织工程技术的发展,组织工程心脏瓣膜被认为是一种潜在的理想的人造瓣膜,具有非常重要的临床应用前景,是目前心脏瓣膜外科领域研究热点之一。本文对近年来组织细胞来源和种植、瓣膜支架材料、体外预适应和动物试验等方面的内容进行了综述,并指出目前研究中所存在的问题。
In the field of cardiac surgery, valve replacement is an effective approach to treat valve disorders,however, all of heart valves can be used clinically have different degrees of impairment. With the development of tissue engineering, tissue-engineered heart valve is considered a potential and perfect valve, which has bright clinical future,and now it has become a hot area of research. In this article, the resource of tissue cells and implantation, valve scaffold, in vitro pre -adaptation testing and in vivo animal experiment results are reviewed and the problems that in the current study are pointed out.
出处
《中国医疗器械信息》
2010年第4期35-43,共9页
China Medical Device Information
关键词
组织工程
心脏瓣膜
动物试验
tissue engineering, cardiac valves, animal testing
