中性粒细胞/淋巴细胞比率对急性心肌梗死患者临床并发症的预测价值

Usefulness of the neutrophil to lymphocyte ratio in predicting complications in patients with acute myocardial infarction

目的:探讨中性粒细胞/淋巴细胞比率(NLR)与急性心肌梗死(AMI)患者临床并发症之间的关系。方法:入选急性ST段抬高心肌梗死(STEMI)患者218例,入院后即刻抽取静脉血查血常规,按中性粒细胞/淋巴细胞比率的大小由小到大将其分为A、B两组,对两组急性心肌梗死并发症发生率进行比较。结果:两组肌钙蛋白峰值分别为(32.5±21.7)ng/ml和(56.8±39.4)ng/ml,B组高于A组,差异具有统计学意义(P<0.01)。心律失常(17.43%和39.45%,P<0.01)、心力衰竭(22.94%和51.38%,P<0.01)及猝死发生率(2.75%和11.01%,P<0.05)B组均显著高于A组,差异具有统计学意义。多元逐步回归分析显示NLR与AMI并发症发生率具有显著的相关性(P<0.05)。结论:中性粒细胞/淋巴细胞比率是急性心肌梗死患者临床并发症的可靠预测指标。

Objective：To investigate the relationship between the neutrophil to lymphocyte ratio and the morbidity of AMI complications.Methods：A total of 218 patients with ST segment elevated myocardial infarction whose blood routines were obtained at the admission were studied.All cases were divided into two groups according to the neuropil to lymphocyte ratio of small to large size.Then we analyzed the morbidity of AMI complications between the two groups.Results：The peak value of cardiac troponin I was higher in group B[（32.5±21.7） ng/ml and （56.8±39.4） ng/ml respectively,P0.01].The incidences of arrhythmia （17.43% and 39.45%,P0.01）,heart failure （22.94% and 51.38%,P0.01） and death （2.75% and 11.01%,P0.05） were also higher in group B.The multivariate stepwise regression analysis showed that the neutrophil to lymphocyte ratio and the morbidity of AMI complications had significant correlation.Conclusion：The neutrophil to lymphocyte ratio was a reliable indicator that can predict morbidity of AMI complications.