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SDF-1/CXCR4生物学轴与肿瘤的研究进展 被引量:1

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摘要 趋化因子是促炎症趋化细胞因子类大家族成员之一,它在许多生理和病理过程中有着很重要的作用。相同的趋化因子可以和许多受体结合,相同的受体也可以和不同的趋化因子结合,而趋化因子受体(CXCR4)是趋化因子(SDF-1)的唯一受体。近年研究发现SDF-1/CXCR4生物学轴在肿瘤侵袭和转移中发挥了重要作用,可作为肿瘤治疗的新靶点。
作者 王红 张轶清
出处 《安徽医学》 2010年第3期282-284,共3页 Anhui Medical Journal
关键词 CXCR4 SDF-1 肿瘤 转移
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