期刊文献+

B淋巴细胞在甲状腺相关性眼病中的作用及其对应治疗新策略 被引量:1

原文传递
导出
摘要 甲状腺相关性眼病(TAO)是一种累及球后结缔组织和眼外肌的自身免疫性疾病,但是其发病机制至今尚不明确。最近的临床和基础研究对该病有了进一步的认识,根据文献中描述TAO的免疫机制、B细胞在该病中所起的作用,并对已有的B细胞抑制剂在多种自身免疫性疾病上的应用进行回顾,推测B细胞抑制剂将成为甲状腺相关性眼病新的治疗方法之一。
作者 王韧琰 钟勇
出处 《中国实用眼科杂志》 CSCD 北大核心 2010年第3期219-222,共4页 Chinese Journal of Practical Ophthalmology
  • 相关文献

参考文献31

  • 1Paul W.Fundamental Immunology.Fifith Edition.Lippincott Williams and Wilkins[J].Philadelphia, 2003 : 270-271.
  • 2Bartley GB, Fatourechi V, Kadrmas EF, et al.The incidence of Graves' ophthalmopathy in Olmsted Country, Minnesota[J].Am J Ophthalmol, 1995,120: 511-517.
  • 3Schotthoefer EO, Wallace DK.Strabismus associated with thyroid eye disease[J].Curr Opin Ophthalmol , 2007,18 : 361-365.
  • 4Andrew GG, Terry JS.Recent insights into the pathogenesis and management of thyroid-associated ophthalmopathy.Current Opinion in Endocrinology[J].Diabetes and Obesity, 2008, 15:446-452.
  • 5Feldon SE, Park DJ, O'Loughlin CW, et al.Autologous T-lymphocytes stimulate proliferation of orbital fibroblasts derived from patients with Graves' ophthalmopathy[J].Invest Ophthalmol Vis Sci , 2005,46: 3913-3921.
  • 6Seema K, Rebecca SB.Relative Overexpression of Macrophage-Derived Cytokines in Orbital Adipose Tissue from Patients with Graves' Ophthalmopathy[J].J Clin Endocrinol Metab , 2003,88 : 4246-4250.
  • 7Lee AK, Terry JS.Expression of Hyaluronan Synthase Messenger Ribonucleic Acids and Their Induction by Interleukin-1b in Human Orbital Fibroblasts: Potential Insight into the Molecular Pathogenesis of Thyroid-Associated Ophthalmopathy [J].J Clin Endocrinol Metab , 1999, 84: 4079-4084.
  • 8Martinez-GL, Brezinschek HP, Burmester GR,et al.Immunopatholic role of B lymphocytes in rheumatoid arthritis:rationale of B cell-directed therapy[J].Autoimmun.Rev, 2006, 5 : 437-442.
  • 9Tedder TF, Engel P.CD20: a regulator of cell-cycle progression of B lymphocytes[J].Immunol Today , 1994, 15 : 450-454.
  • 10Keystone EC.Safety issues related to emerging therapies for rheumatoid arthritis[J].Clin Exp Rheumatol, 2004, 22:148-150.

同被引文献15

引证文献1

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部