使用计算机终端及不同休息方案对眼表性状的影响

Effects of work-rest schedules on ocular surface for computer-terminal reader

目的研究使用计算机终端及不同的休息方案对眼表性状的影响。方法30名受试者均接受5种不同阅读方案：1．连续计算机终端阅读2h后休息10min。（2）连续书本阅读2h后休息10min。（3）连续计算机终端阅读1h后休息10min（休息1方案）。（4）计算机终端阅读总时间1h，每30min间隔休息5min（休息2方案）。（5）计算机终端阅读总时间1h，每15min间隔休息2min（休息3方案）。每次阅读前后分别检查眼部泪膜破裂时间（Breakup Time，BUT）、基础泪液分泌试验（Schirmer I test，Sit）、角膜荧光素染色（Fluoreseein Staining，FL）、虎红（Rose Bangle，Rb）染色、结膜印迹细胞（Impression Cytology，IC）检查。结果（1）连续2h计算机终端阅读后较书本阅读更易出现BUT缩短、SIt值减少、FL及Rb染色评分增加（P〈0．05）。（2）连续计算机终端阅读2h较1h更易出现BUT缩短SIt值减少、FL及Rb染色评分增加（P〈0．05）.（3）3种休息方案之间的BUT、FL、Rb染色之间的差异具统计学意义（P〈0．05），休息3方案优于其它方案。结论使用计算机终端阅读较书本阅读更易对眼表性状产生影响，并随时间的不同出现差异。三种不同休息方案比较，每使用计算机终端阅读15min间隔休息2min（休息3方案）对眼表性状影响最小。

Objective To evaluate the effects of work-rest schedules on ocular surface for computer terminal readers.Methods Thirty participants underwent 5 reading assignments： （ 1 ） 2-hour continuous computer-based reading, followed by 10 minutes rest; （2） 2-hour continuous book-based reading, followed by 10 minutes rest; （3） 1 hour continuous computer-based reading followed by 10 minutes rest （work-rest schedule 1, WS 1 ） ; （4） 1-hour computer-based reading with a 5 -min break in every 30 mins （WS2） ; （5） 1-hour computer-based reading with a 2-min break in every 15 mins （WS3）.Before and after reading assignments （after the rest）, Break-Up time （BUT）, Schirmer I test （Sit）, Fluorescent test （FL）, rose bangle （Rb）, conjunctival impression cytology （IC） were measured.Results After reading assigrunent, people with assignment 1 were more likely to have a shorter BUT, decreased Sit, increased FL and Rb score than in people with assignment 2 （all with P〈0.05 ）.These changes were more profound in people with assignment 1 than in people with assignment 3 （WS 1 ） （all with P〈 0.05 ）.These changes were more profound in people with WS 1/WS2 than in people with WS3 （all with P〈0.05 ）.Conclusions Computer-based reading is more likely to affect the stability of ocular surface than book-based reading.The stability decreases with longer reading time.Compared with WS1 and WS2, WS3 is the optimal reading schedule with least impact on ocular surface.