吉西他滨同步三维适形放疗治疗老年晚期非小细胞肺癌的护理

The nursing experience of treating the advanced non-small cell lung cancer of the elderly by Gemcitabine combined with three-dimensional conformal radiotherapy

目的总结吉西他滨同步三维适形放疗治疗老年晚期非小细胞肺癌的护理经验。方法64例老年晚期非小细胞肺癌在三维适形放疗1周后，用吉西他滨0．8—1g／m2静脉滴注，在放疗第1天、8天、15天、22天以周剂量方式进行治疗。用肿瘤治疗毒性反应评分标准进行观察评估，并给予医疗护理干预。结果64例患者中发生不同程度毒性反应，白细胞减少、血小板下降、恶心、呕吐，放射性肺炎、食管炎等发生率较高，但均完成治疗计划。结论做好心理护理、预防感染、毒性反应观察与护理是控制和减少毒性反应发生的必要手段，可以保证治疗方案顺利进行。

Objective：To summarize the nursing experience of treating the advanced non-small cell lung cancer of the elderly by Gemcitabine combined with three-dimensional conformal radiotherapy. Methods： Gemcitabine 0.8 - 1 g/m2 intravenous drip was given at d1, d8, d15, d22 one week after 64 elder patients with advanced non-small cell lung cancer （NSCLC） were treated by three-dimensional conformal radiotherapy. One cycle consisted of one week. Results： 64 cases of NSCLC showed toxic reaction in different degrees. The incidence rate of WBC descent, platelet decreasing, nausea, vomi- ting, radiation pneumonitis and esophagitis is higher, but all patients achieved the treatment plan successfully. Conclusion： To make good psychology nursing, preventing infection, observation and nursing of toxicity effect become necessary means of controlling and reducing toxicity. It can guarantee the smooth progress of the treatment plan.