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脂微球前列腺素E_1治疗糖尿病性周围神经病变临床观察

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摘要 目的:研究脂微球前列腺素E1治疗糖尿病周围神经病变的临床疗效及观察其不良反应。方法:糖尿病合并周围神经病变的30例患者,给予Lipo-PGE110μg/日。对照组32例给予维生素B110mg/日、维生素B120.5mg/日。结果:治疗组临床疗效、神经传导速度改善明显优于对照组,两组间有明显差异(P<0.05)。用药过程中未见明显不良反应。结论:Lipo-PGE1是治疗糖尿病周围神经病变有效且安全的药物。
作者 路娜 郑华
出处 《中国社区医师(医学专业)》 2010年第9期85-85,共1页
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  • 1Cameron N E,Eaton S E,Cotter M A, et al . Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy[J]. Diabetologia, 2001,44(11) : 1973-1988.
  • 2Haler M C, Ivey F M, Gyure K A, et al. Thrombomodulin deficiency in human diabetic nerve microvasculature [J]. Diabetes, 2002,51(6): 1957-1963.
  • 3Aso Y, Fujiwara Y, Tayama K, a al. Elevation of von Willebrand factor in plasma in diabetic patients with neuropathic foot ulceration[J]. Diabet Med, 2002,19(1) : 19-26.
  • 4Nakayama M, Nakamaru J, Hamada Y, a al . Aldose reductase inhibition ameliorates pupillary light reflex and F-wave latency in patients with mild diabetic neuropathy[J]. Diabetes Care,2001,24(6) : 1093-1098.
  • 5Zochodne D W. Diabetic neuropathies : features and mechanisms[J]. Brain Pathol,1999,9(2) :369-391.
  • 6Verrotti A,Giuva P T, Morgese G, et al . New trends in the etipathogenesis of diabetic peripheral neuropathy[J]. J Child Neurol, 2001,16(6) : 389-394.
  • 7Conti G, Scarpini E, Baron P, mal . Macrophage infiltration and death in the nerve during the early phases of experimental diabetic neuropathy: a process concomitant with endoneurial induction of IL-lbeta and p75NTR[J]. J Neurol Sci, 2002,195(1) : 35-40.
  • 8Skundric D S, Dai R, James J, mal. Activation of IL-1 signaling pathway in Schwann cells during diabetic neuropathy [J]. AnnNYAcadSci, 2002,958(2): 393-398.
  • 9Rask C A. Biological actions of nerve growths factors in the peripheral nervous system[J]. Eur neurol, 1999,41( Supple 1) :14-19.
  • 10Femyhough P, Diemel L T, Tomlinson D R, a al. Target tissue production and axonal transport of neurotrophin-3 are reduced in steptozotocin-dibetic rats[J]. Diabetologia,1998,41(3) :300-306.

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