骨组织工程血管化的研究进展

Research progress of the vascularization of the bone tissue engineering

血管化是组织工程骨成活的关键,组织工程骨的血管化过程与生理情况下的血管发生相似,但又有其独特性,并受多种因素影响。基于对组织工程骨血管化过程的认识,研究者通过联合细胞培养、促血管化生长因子、显微外科等方法重建血运。本文综述了当前骨组织工程的血管化研究进展。

Vascularization is essential to the survival of the tissue engineering bone. The course of vascularization of the tissue engineering bone resembles that under the physical conditions,but takes on its own peculiarity and is influenced by multiple factors. Based on the current understandings of the vascularization of the tissue engineering bone,researchers have utilized a few methods,such as combined cell culture/vascular growth factors/microsurgery,to achieve revascularization in it. This article summarized current progress on the research of vascularization of the bone tissue engineering.