孕妇肥胖与死产关系的Meta分析

Maternal obesity and risk of stillbirth: a meta-analysis

目的:探讨孕妇超重或肥胖与死产的关系。方法:采用RevMan4.2.10版本软件中的Meta分析,检索Pubmed文献数据库中1980年～2008年有关死产的孕妇超重或肥胖因素文献,并进行定量综合分析。结果:经检索、筛选后纳入的有关死产的孕妇超重或肥胖因素文献11篇;经异质性检验,采用固定效应模型、随机效应模型进行定量综合分析。综合结果表明孕妇超重、孕妇肥胖对死产的影响OR值分别为1.21(95%CI:1.05-1.40)、1.69(95%CI:1.51-1.90)。结论:孕妇因超重或肥胖的死产率明显高于正常体重孕妇。

Objective：To investigate the correlation between maternal overweight/obesity and stillbirth. Methods： We applied a meta-analysis in software of RevMan4.2.10 version, searched and collected the literature on overweigh pregnant women or the relationship between obesity and stillbirth published from 1980 to 2008 in PubMed, which was made a comprehensive and quantitative analysis. Results： The search included the screening of pregnant women are overweight or obese stillborn factors; by the heterogeneity test, using a fixed effect model, random effects model for quantitative analysis. Conclusion pregnant women are overweight or obese stillbirth rate was significantly higher than normal-weight pregnant women. After searching and screening of the literature, 11 were about overweigh pregnant women with stillbirth or obesity. Consolidated results showed that overweight/obesity pregnant women made a notable impact on stillbirth： the values of OR were1.21 （95%CI：1.05-1.40） and 1.69（95%CI：1.51-1.90）. Conclusions： The stillbirth rates of pregnant women due to overweight or obese were significantly higher than those of pregnant women with normal weight.